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Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
Heat shock factor (Hsf1) regulates the expression of molecular chaperones to maintain protein homeostasis. Despite its central role in stress resistance, disease and aging, the mechanisms that control Hsf1 activity remain unresolved. Here we show that in budding yeast, Hsf1 basally associates with t...
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| Publicado no: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127643/ https://ncbi.nlm.nih.gov/pubmed/27831465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18638 |
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