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Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response
Protein AMPylation is a conserved posttranslational modification with emerging roles in endoplasmic reticulum homeostasis. However, the range of substrates and cell biological consequences of AMPylation remain poorly defined. We expressed human and Caenorhabditis elegans AMPylation enzymes—huntingti...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240723/ https://ncbi.nlm.nih.gov/pubmed/28031489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619234114 |
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