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The Chaperone BAG6 Captures Dislocated Glycoproteins in the Cytosol

Secretory and membrane (glyco)proteins are subject to quality control in the endoplasmic reticulum (ER) to ensure that only functional proteins reach their destination. Proteins deemed terminally misfolded and hence functionally defective may be dislocated to the cytosol, where the proteasome degrad...

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Detalles Bibliográficos
Main Authors: Claessen, Jasper H. L., Sanyal, Sumana, Ploegh, Hidde L
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940849/
https://ncbi.nlm.nih.gov/pubmed/24594942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090204
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