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The Chaperone BAG6 Captures Dislocated Glycoproteins in the Cytosol

Secretory and membrane (glyco)proteins are subject to quality control in the endoplasmic reticulum (ER) to ensure that only functional proteins reach their destination. Proteins deemed terminally misfolded and hence functionally defective may be dislocated to the cytosol, where the proteasome degrad...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Claessen, Jasper H. L., Sanyal, Sumana, Ploegh, Hidde L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940849/
https://ncbi.nlm.nih.gov/pubmed/24594942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090204
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