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A Viral Deubiquitylating Enzyme Restores Dislocation of Substrates from the Endoplasmic Reticulum (ER) in Semi-intact Cells

Terminally misfolded glycoproteins are ejected from the endoplasmic reticulum (ER) to the cytosol and are destroyed by the ubiquitin proteasome system. A dominant negative version of the deubiquitylating enzyme Yod1 (Yod1C160S) causes accumulation of dislocation substrates in the ER. Failure to remo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sanyal, Sumana, Claessen, Jasper H. L., Ploegh, Hidde L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390634/
https://ncbi.nlm.nih.gov/pubmed/22619172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365312
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