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BAT3 Guides Misfolded Glycoproteins Out of the Endoplasmic Reticulum

Secretory and membrane proteins that fail to acquire their native conformation within the lumen of the Endoplasmic Reticulum (ER) are usually targeted for ubiquitin-dependent degradation by the proteasome. How partially folded polypeptides are kept from aggregation once ejected from the ER into the...

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Detalhes bibliográficos
Main Authors: Claessen, Jasper H. L., Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234288/
https://ncbi.nlm.nih.gov/pubmed/22174835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028542
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