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Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation

Heat shock factor (Hsf1) regulates the expression of molecular chaperones to maintain protein homeostasis. Despite its central role in stress resistance, disease and aging, the mechanisms that control Hsf1 activity remain unresolved. Here we show that in budding yeast, Hsf1 basally associates with t...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Zheng, Xu, Krakowiak, Joanna, Patel, Nikit, Beyzavi, Ali, Ezike, Jideofor, Khalil, Ahmad S, Pincus, David
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127643/
https://ncbi.nlm.nih.gov/pubmed/27831465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18638
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