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Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation

Heat shock factor (Hsf1) regulates the expression of molecular chaperones to maintain protein homeostasis. Despite its central role in stress resistance, disease and aging, the mechanisms that control Hsf1 activity remain unresolved. Here we show that in budding yeast, Hsf1 basally associates with t...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Zheng, Xu, Krakowiak, Joanna, Patel, Nikit, Beyzavi, Ali, Ezike, Jideofor, Khalil, Ahmad S, Pincus, David
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127643/
https://ncbi.nlm.nih.gov/pubmed/27831465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18638
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