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Evaluating side effects of nanoparticle‐mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis

RNA interference has immense potential to modulate cell functions. However, effective delivery of small interfering RNA (siRNA) while avoiding deleterious side effects has proven challenging. This study investigates both intended and unintended effects of diblock copolymer nanoparticle (NP) delivery...

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Foilsithe in:Bioeng Transl Med
Main Authors: Malcolm, Dominic W., Sorrells, Janet E., Van Twisk, Daniel, Thakar, Juilee, Benoit, Danielle S. W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125403/
https://ncbi.nlm.nih.gov/pubmed/27981244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10035
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