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Degradable Poly(ethylene glycol) (PEG)-based Hydrogels for Spatiotemporal Control of siRNA/Nanoparticle Delivery

Despite great therapeutic potential and development of a repertoire of delivery approaches addressing degradation and cellular uptake limitations, small interfering RNA (siRNA) exhibits poorly controlled tissue-specific localization. To overcome this hurdle, siRNA was complexed to nanoparticles (siR...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Wang, Yuchen, Zhang, Sue, Benoit, Danielle S.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183067/
https://ncbi.nlm.nih.gov/pubmed/30077736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.002
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