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Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing
Despite great potential, delivery remains as the most significant barrier to the widespread use of siRNA therapeutics. siRNA has delivery limitations due to susceptibility to RNase degradation, low cellular uptake, and poor tissue-specific localization. Here, we report the development of a hybrid na...
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| Veröffentlicht in: | Biomaterials |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599180/ https://ncbi.nlm.nih.gov/pubmed/28601703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.06.001 |
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