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Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery

Receptor-mediated, cell-specific delivery of siRNA enables silencing of target genes in specific tissues, opening the door to powerful therapeutic options for a multitude of diseases. However, development of delivery systems capable of targeted and effective siRNA delivery typically requires multipl...

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Detalhes bibliográficos
Main Authors: Benoit, Danielle S.W., Srinivasan, Selvi, Shubin, Andrew D., Stayton, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147305/
https://ncbi.nlm.nih.gov/pubmed/21634800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm200485b
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