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Synthesis of Polymer-Lipid Nanoparticles by Microfluidic Focusing for siRNA Delivery
Polyethylenimine (PEI) as a cationic polymer is commonly used as a carrier for gene delivery. PEI-800 is less toxic than PEI-25K but it is also less efficient. A novel nanocarrier was developed by combining PEI-800 with a pH-sensitive lipid to form polymer-lipid hybrid nanoparticles (P/LNPs). They w...
Shranjeno v:
| izdano v: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6274485/ https://ncbi.nlm.nih.gov/pubmed/27763492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101314 |
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