Targeted Co-Delivery of siRNA and Methotrexate for Tumor Therapy via Mixed Micelles

A combination of chemotherapeutic drugs and siRNA is emerging as a new modality for cancer therapy. A safe and effective carrier platform is needed for combination drug delivery. Here, a functionalized mixed micelle-based delivery system was developed for targeted co-delivery of methotrexate (MTX) a...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Hao, Fei, Lee, Robert J., Yang, Chunmiao, Zhong, Lihuang, Sun, Yating, Dong, Shiyan, Cheng, Ziyuan, Teng, Lirong, Meng, Qingfan, Lu, Jiahui, Xie, Jing, Teng, Lesheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409946/
https://ncbi.nlm.nih.gov/pubmed/30795589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020092
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