Hybrid Lipid-Polymer Nanoparticles for Sustained siRNA Delivery and Gene Silencing

The development of controlled-release nanoparticle (NP) technologies has great potential to further improve the therapeutic efficacy of RNA interference (RNAi), by prolonging the release of small interfering RNA (siRNA) for sustained, long-term gene silencing. Herein, we present a NP platform with s...

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Main Authors: Shi, Jinjun, Xu, Yingjie, Xu, Xiaoyang, Zhu, Xi, Pridgen, Eric, Wu, Jun, Votruba, Alexander R., Archana, Swami, Zetter, Bruce R., Farokhzad, Omid C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077924/
https://ncbi.nlm.nih.gov/pubmed/24650883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.03.006
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