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Human serum albumin-coated lipid nanoparticles for delivery of siRNA to breast cancer

Human serum albumin (HSA)-coated lipid nanoparticles (HSA-LNPs) loaded with phrGFP-targeted siRNA (HSA-LNPs-siRNA) were prepared and evaluated for gene downregulation effect in phrGFP-transfected breast cancer cells and the corresponding xenograft tumor model. HSA-LNPs-siRNA were successfully prepar...

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Hlavní autoři: Piao, Longzhu, Li, Hong, Teng, Lesheng, Yung, Bryant C., Sugimoto, Yasuro, Brueggemeier, Robert W., Lee, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605725/
https://ncbi.nlm.nih.gov/pubmed/22542825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.03.008
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