Human serum albumin-coated lipid nanoparticles for delivery of siRNA to breast cancer

Human serum albumin (HSA)-coated lipid nanoparticles (HSA-LNPs) loaded with phrGFP-targeted siRNA (HSA-LNPs-siRNA) were prepared and evaluated for gene downregulation effect in phrGFP-transfected breast cancer cells and the corresponding xenograft tumor model. HSA-LNPs-siRNA were successfully prepar...

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Bibliografiske detaljer
Main Authors: Piao, Longzhu, Li, Hong, Teng, Lesheng, Yung, Bryant C., Sugimoto, Yasuro, Brueggemeier, Robert W., Lee, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605725/
https://ncbi.nlm.nih.gov/pubmed/22542825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.03.008
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