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Development of a novel endosomolytic diblock copolymer for siRNA delivery
The gene knockdown activity of small interfering RNA (siRNA) has led to their use as target validation tools and as potential therapeutics for a variety of diseases. The delivery of these double-stranded RNA macromolecules has proven to be challenging, however, and in many cases, is a barrier to the...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110267/ https://ncbi.nlm.nih.gov/pubmed/18973780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.10.004 |
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