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Evaluating side effects of nanoparticle‐mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis

RNA interference has immense potential to modulate cell functions. However, effective delivery of small interfering RNA (siRNA) while avoiding deleterious side effects has proven challenging. This study investigates both intended and unintended effects of diblock copolymer nanoparticle (NP) delivery...

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Detalhes bibliográficos
Publicado no:Bioeng Transl Med
Main Authors: Malcolm, Dominic W., Sorrells, Janet E., Van Twisk, Daniel, Thakar, Juilee, Benoit, Danielle S. W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125403/
https://ncbi.nlm.nih.gov/pubmed/27981244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10035
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