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Evaluating side effects of nanoparticle‐mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis

RNA interference has immense potential to modulate cell functions. However, effective delivery of small interfering RNA (siRNA) while avoiding deleterious side effects has proven challenging. This study investigates both intended and unintended effects of diblock copolymer nanoparticle (NP) delivery...

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Vydáno v:Bioeng Transl Med
Hlavní autoři: Malcolm, Dominic W., Sorrells, Janet E., Van Twisk, Daniel, Thakar, Juilee, Benoit, Danielle S. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125403/
https://ncbi.nlm.nih.gov/pubmed/27981244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10035
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