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Human T lymphocytes Bioactivate Heterocyclic Aromatic Amines by Forming DNA adducts

Heterocyclic aromatic amines (HAA) are formed in cooked meat, poultry and fish but also arise in tobacco smoke and exhaust gases. HAA are potential human carcinogens, which require metabolic activation to exert their genotoxicity. Human tissues can bioactivate HAA to produce reactive intermediates t...

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Dades bibliogràfiques
Publicat a:Environ Mol Mutagen
Autors principals: Bellamri, Medjda, Le Hegarat, Ludovic, Vernhet, Laurent, Baffet, Georges, Turesky, Robert J, Langouët, Sophie
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123841/
https://ncbi.nlm.nih.gov/pubmed/27801952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22059
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