Human T lymphocytes Bioactivate Heterocyclic Aromatic Amines by Forming DNA adducts

Heterocyclic aromatic amines (HAA) are formed in cooked meat, poultry and fish but also arise in tobacco smoke and exhaust gases. HAA are potential human carcinogens, which require metabolic activation to exert their genotoxicity. Human tissues can bioactivate HAA to produce reactive intermediates t...

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Библиографические подробности
Опубликовано в: :Environ Mol Mutagen
Главные авторы: Bellamri, Medjda, Le Hegarat, Ludovic, Vernhet, Laurent, Baffet, Georges, Turesky, Robert J, Langouët, Sophie
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123841/
https://ncbi.nlm.nih.gov/pubmed/27801952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22059
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