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Bioactivation of Heterocyclic Aromatic Amines by UDP Glucuronosyltransferases
2-Amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) are carcinogenic heterocyclic aromatic amines (HAA) that arise during the burning of tobacco and cooking of meats. UDP-glucuronosyltransferases (UGT) detoxicate many procarcinogens and their metabolites....
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| 出版年: | Chem Res Toxicol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868641/ https://ncbi.nlm.nih.gov/pubmed/27032077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00046 |
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