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Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity

Heterocyclic aromatic amines (HAAs) are mutagens and potential human carcinogens. Our group and others have demonstrated that HAAs may also produce selective dopaminergic neurotoxicity, potentially relevant to Parkinson’s disease (PD). The goal of this study was to elucidate mechanisms of HAA-induce...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Lawana, Vivek, Um, Se Young, Rochet, Jean-Christophe, Turesky, Robert J, Shannahan, Jonathan H, Cannon, Jason R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944224/
https://ncbi.nlm.nih.gov/pubmed/31562763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz210
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