Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity

Heterocyclic aromatic amines (HAAs) are mutagens and potential human carcinogens. Our group and others have demonstrated that HAAs may also produce selective dopaminergic neurotoxicity, potentially relevant to Parkinson’s disease (PD). The goal of this study was to elucidate mechanisms of HAA-induce...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Lawana, Vivek, Um, Se Young, Rochet, Jean-Christophe, Turesky, Robert J, Shannahan, Jonathan H, Cannon, Jason R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Neurotoxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944224/
https://ncbi.nlm.nih.gov/pubmed/31562763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz210
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