Human T lymphocytes Bioactivate Heterocyclic Aromatic Amines by Forming DNA adducts

Heterocyclic aromatic amines (HAA) are formed in cooked meat, poultry and fish but also arise in tobacco smoke and exhaust gases. HAA are potential human carcinogens, which require metabolic activation to exert their genotoxicity. Human tissues can bioactivate HAA to produce reactive intermediates t...

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Bibliografiske detaljer
Udgivet i:Environ Mol Mutagen
Main Authors: Bellamri, Medjda, Le Hegarat, Ludovic, Vernhet, Laurent, Baffet, Georges, Turesky, Robert J, Langouët, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123841/
https://ncbi.nlm.nih.gov/pubmed/27801952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22059
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