Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome

Prader–Willi syndrome (PWS), a neurodevelopmental disorder caused by loss of paternal gene expression from 15q11–q13, is characterised by growth retardation, hyperphagia and obesity. However, as single gene mutation mouse models for this condition display an incomplete spectrum of the PWS phenotype,...

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Vydáno v:J Endocrinol
Hlavní autoři: Golding, David M, Rees, Daniel J, Davies, Jennifer R, Relkovic, Dinko, Furby, Hannah V, Guschina, Irina A, Hopkins, Anna L, Davies, Jeffrey S, Resnick, James L, Isles, Anthony R, Wells, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: Bioscientifica Ltd 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118940/
https://ncbi.nlm.nih.gov/pubmed/27799465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0367
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