Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome

Prader–Willi syndrome (PWS), a neurodevelopmental disorder caused by loss of paternal gene expression from 15q11–q13, is characterised by growth retardation, hyperphagia and obesity. However, as single gene mutation mouse models for this condition display an incomplete spectrum of the PWS phenotype,...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Endocrinol
Главные авторы: Golding, David M, Rees, Daniel J, Davies, Jennifer R, Relkovic, Dinko, Furby, Hannah V, Guschina, Irina A, Hopkins, Anna L, Davies, Jeffrey S, Resnick, James L, Isles, Anthony R, Wells, Timothy
Формат: Artigo
Язык:Inglês
Опубликовано: Bioscientifica Ltd 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118940/
https://ncbi.nlm.nih.gov/pubmed/27799465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0367
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы