Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome

Prader–Willi syndrome (PWS), a neurodevelopmental disorder caused by loss of paternal gene expression from 15q11–q13, is characterised by growth retardation, hyperphagia and obesity. However, as single gene mutation mouse models for this condition display an incomplete spectrum of the PWS phenotype,...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Golding, David M, Rees, Daniel J, Davies, Jennifer R, Relkovic, Dinko, Furby, Hannah V, Guschina, Irina A, Hopkins, Anna L, Davies, Jeffrey S, Resnick, James L, Isles, Anthony R, Wells, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118940/
https://ncbi.nlm.nih.gov/pubmed/27799465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0367
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