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Prader–Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT(2C)R-mediated response inhibition

Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11–q13. In addition to endocrine and developmental issues, PWS presents with behavioural problems including stereotyped behaviour, impulsiven...

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Dades bibliogràfiques
Publicat a:Hum Mol Genet
Autors principals: Davies, Jennifer R, Wilkinson, Lawrence S, Isles, Anthony R, Humby, Trevor
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737253/
https://ncbi.nlm.nih.gov/pubmed/31087031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz100
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