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Prader–Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT(2C)R-mediated response inhibition

Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11–q13. In addition to endocrine and developmental issues, PWS presents with behavioural problems including stereotyped behaviour, impulsiven...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Davies, Jennifer R, Wilkinson, Lawrence S, Isles, Anthony R, Humby, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737253/
https://ncbi.nlm.nih.gov/pubmed/31087031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz100
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