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Prader–Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT(2C)R-mediated response inhibition

Prader–Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11–q13. In addition to endocrine and developmental issues, PWS presents with behavioural problems including stereotyped behaviour, impulsiven...

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Détails bibliographiques
Publié dans:Hum Mol Genet
Auteurs principaux: Davies, Jennifer R, Wilkinson, Lawrence S, Isles, Anthony R, Humby, Trevor
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737253/
https://ncbi.nlm.nih.gov/pubmed/31087031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz100
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