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When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

Nanoformulations have become important tools for modifying drug disposition, be it from the perspective of enabling prolonged drug release, protecting the drug molecule from metabolism, or achieving targeted delivery. When examining the in vivo pharmacokinetic properties of these formulations, most...

詳細記述

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書誌詳細
出版年:Drug Metab Dispos
主要な著者: Stern, Stephan T., Martinez, Marilyn N., Stevens, David M.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118636/
https://ncbi.nlm.nih.gov/pubmed/27670412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.073148
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