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When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

Nanoformulations have become important tools for modifying drug disposition, be it from the perspective of enabling prolonged drug release, protecting the drug molecule from metabolism, or achieving targeted delivery. When examining the in vivo pharmacokinetic properties of these formulations, most...

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Detaylı Bibliyografya
Yayımlandı:Drug Metab Dispos
Asıl Yazarlar: Stern, Stephan T., Martinez, Marilyn N., Stevens, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118636/
https://ncbi.nlm.nih.gov/pubmed/27670412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.073148
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