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When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

Nanoformulations have become important tools for modifying drug disposition, be it from the perspective of enabling prolonged drug release, protecting the drug molecule from metabolism, or achieving targeted delivery. When examining the in vivo pharmacokinetic properties of these formulations, most...

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Bibliografiske detaljer
Udgivet i:Drug Metab Dispos
Main Authors: Stern, Stephan T., Martinez, Marilyn N., Stevens, David M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118636/
https://ncbi.nlm.nih.gov/pubmed/27670412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.073148
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