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Notch signaling promotes nephrogenesis by downregulating Six2
During nephrogenesis, multipotent mesenchymal nephron progenitors develop into distinct epithelial segments. Each nephron segment has distinct cell types and physiological function. In the current model of kidney development, Notch signaling promotes the formation of proximal tubules and represses t...
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| Pubblicato in: | Development |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117151/ https://ncbi.nlm.nih.gov/pubmed/27633993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143503 |
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