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Notch signaling promotes nephrogenesis by downregulating Six2

During nephrogenesis, multipotent mesenchymal nephron progenitors develop into distinct epithelial segments. Each nephron segment has distinct cell types and physiological function. In the current model of kidney development, Notch signaling promotes the formation of proximal tubules and represses t...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Chung, Eunah, Deacon, Patrick, Marable, Sierra, Shin, Juhyun, Park, Joo-Seop
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117151/
https://ncbi.nlm.nih.gov/pubmed/27633993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143503
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