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Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation
Notch signaling plays important roles during mammalian nephrogenesis. To investigate whether Notch regulates nephron segmentation, we performed Notch loss-of-function and gain-of-function studies in developing nephrons in mice. Contrary to the previous notion that Notch signaling promotes the format...
Uloženo v:
| Vydáno v: | Development |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists Ltd
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769624/ https://ncbi.nlm.nih.gov/pubmed/29113990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.156661 |
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