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Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome

Different nephron tubule segments perform distinct physiological functions, collectively acting as a blood filtration unit. Dysfunction of the proximal tubule segment can lead to Fanconi renotubular syndrome (FRTS), with major symptoms such as excess excretion of water, glucose, and phosphate in the...

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Publicado en:JCI Insight
Main Authors: Marable, Sierra S., Chung, Eunah, Adam, Mike, Potter, S. Steven, Park, Joo-Seop
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124415/
https://ncbi.nlm.nih.gov/pubmed/30046000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97497
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