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Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome
Different nephron tubule segments perform distinct physiological functions, collectively acting as a blood filtration unit. Dysfunction of the proximal tubule segment can lead to Fanconi renotubular syndrome (FRTS), with major symptoms such as excess excretion of water, glucose, and phosphate in the...
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| Veröffentlicht in: | JCI Insight |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6124415/ https://ncbi.nlm.nih.gov/pubmed/30046000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97497 |
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