Glycation potentiates neurodegeneration in models of Huntington’s disease

Protein glycation is an age-dependent posttranslational modification associated with several neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. By modifying amino-groups, glycation interferes with folding of proteins, increasing their aggregation potential. Here, we studied...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Vicente Miranda, Hugo, Gomes, Marcos António, Branco-Santos, Joana, Breda, Carlo, Lázaro, Diana F., Lopes, Luísa Vaqueiro, Herrera, Federico, Giorgini, Flaviano, Outeiro, Tiago Fleming
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114697/
https://ncbi.nlm.nih.gov/pubmed/27857176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36798
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares