Glycation potentiates neurodegeneration in models of Huntington’s disease

Protein glycation is an age-dependent posttranslational modification associated with several neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. By modifying amino-groups, glycation interferes with folding of proteins, increasing their aggregation potential. Here, we studied...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vicente Miranda, Hugo, Gomes, Marcos António, Branco-Santos, Joana, Breda, Carlo, Lázaro, Diana F., Lopes, Luísa Vaqueiro, Herrera, Federico, Giorgini, Flaviano, Outeiro, Tiago Fleming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114697/
https://ncbi.nlm.nih.gov/pubmed/27857176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados