Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...

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發表在:Nat Commun
Main Authors: Mouillesseaux, Kevin P., Wiley, David S., Saunders, Lauren M., Wylie, Lyndsay A., Kushner, Erich J., Chong, Diana C., Citrin, Kathryn M., Barber, Andrew T., Park, Youngsook, Kim, Jun-Dae, Samsa, Leigh Ann, Kim, Jongmin, Liu, Jiandong, Jin, Suk-Won, Bautch, Victoria L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114582/
https://ncbi.nlm.nih.gov/pubmed/27834400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13247
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