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Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Mouillesseaux, Kevin P., Wiley, David S., Saunders, Lauren M., Wylie, Lyndsay A., Kushner, Erich J., Chong, Diana C., Citrin, Kathryn M., Barber, Andrew T., Park, Youngsook, Kim, Jun-Dae, Samsa, Leigh Ann, Kim, Jongmin, Liu, Jiandong, Jin, Suk-Won, Bautch, Victoria L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114582/
https://ncbi.nlm.nih.gov/pubmed/27834400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13247
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