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Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6
Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114582/ https://ncbi.nlm.nih.gov/pubmed/27834400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13247 |
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