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Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation

Blood vessel formation requires dynamic movements of endothelial cells (ECs) within sprouts. The cytoskeleton regulates migratory polarity, and centrosomes organize the microtubule cytoskeleton. However, it is not well understood how excess centrosomes, commonly found in tumor stromal cells, affect...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Kushner, Erich J., Ferro, Luke S., Yu, Zhixian, Bautch, Victoria L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907724/
https://ncbi.nlm.nih.gov/pubmed/27099371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-09-0645
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