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Excess centrosomes disrupt endothelial cell migration via centrosome scattering
Supernumerary centrosomes contribute to spindle defects and aneuploidy at mitosis, but the effects of excess centrosomes during interphase are poorly understood. In this paper, we show that interphase endothelial cells with even one extra centrosome exhibit a cascade of defects, resulting in disrupt...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107782/ https://ncbi.nlm.nih.gov/pubmed/25049273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311013 |
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