Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...

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Publicado no:Nat Commun
Main Authors: Mouillesseaux, Kevin P., Wiley, David S., Saunders, Lauren M., Wylie, Lyndsay A., Kushner, Erich J., Chong, Diana C., Citrin, Kathryn M., Barber, Andrew T., Park, Youngsook, Kim, Jun-Dae, Samsa, Leigh Ann, Kim, Jongmin, Liu, Jiandong, Jin, Suk-Won, Bautch, Victoria L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114582/
https://ncbi.nlm.nih.gov/pubmed/27834400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13247
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