ER71 acts downstream of BMP, Notch and Wnt signaling in blood and vessel progenitor specification

FLK1 expressing (FLK1(+)) mesoderm generates blood and vessels. Here, we show that combined BMP, Notch and Wnt signaling is necessary for efficient FLK1(+) mesoderm formation from embryonic stem (ES) cells. Inhibition of BMP, Notch and Wnt signaling pathways greatly decreased the generation of FLK1(...

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Detalhes bibliográficos
Main Authors: Lee, Dongjun, Park, Changwon, Lee, Ho, Lugus, Jesse J., Kim, Seok Hyung, Arentson, Elizabeth, Chung, Yun Shin, Gomez, Gustavo, Kyba, Michael, Lin, Shuo, Janknecht, Ralf, Lim, Dae-Sik, Choi, Kyunghee
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683414/
https://ncbi.nlm.nih.gov/pubmed/18462699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.03.008
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