Developmental pathways in colon cancer: Crosstalk between WNT, BMP, Hedgehog and Notch

A hallmark of cancer is reactivation/alteration of pathways that control cellular differentiation during developmental processes. Evidence indicates that WNT, Notch, BMP and Hedgehog pathways have a role in normal epithelial cell differentiation, and that alterations in these pathways accompany esta...

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Bibliographic Details
Main Authors: Bertrand, Fred E., Angus, C. William, Partis, William J., Sigounas, George
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552917/
https://ncbi.nlm.nih.gov/pubmed/23032367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22134
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