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Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
Kidney fibrosis is the histological manifestation of functional decline in the kidney. Fibrosis is a reactive process that develops in response to excessive epithelial injury and inflammation. Here, we describe how three key developmental signalling pathways—Notch, Wnt and Hedgehog—are reactivated i...
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| Udgivet i: | Nat Rev Nephrol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529143/ https://ncbi.nlm.nih.gov/pubmed/27140856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2016.54 |
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