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Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog

Kidney fibrosis is the histological manifestation of functional decline in the kidney. Fibrosis is a reactive process that develops in response to excessive epithelial injury and inflammation. Here, we describe how three key developmental signalling pathways—Notch, Wnt and Hedgehog—are reactivated i...

詳細記述

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書誌詳細
出版年:Nat Rev Nephrol
主要な著者: Edeling, Maria, Ragi, Grace, Huang, Shizheng, Pavenstädt, Hermann, Susztak, Katalin
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529143/
https://ncbi.nlm.nih.gov/pubmed/27140856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2016.54
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