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ER71 acts downstream of BMP, Notch and Wnt signaling in blood and vessel progenitor specification
FLK1 expressing (FLK1(+)) mesoderm generates blood and vessels. Here, we show that combined BMP, Notch and Wnt signaling is necessary for efficient FLK1(+) mesoderm formation from embryonic stem (ES) cells. Inhibition of BMP, Notch and Wnt signaling pathways greatly decreased the generation of FLK1(...
Tallennettuna:
Päätekijät: | , , , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2008
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683414/ https://ncbi.nlm.nih.gov/pubmed/18462699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.03.008 |
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