Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Mouillesseaux, Kevin P., Wiley, David S., Saunders, Lauren M., Wylie, Lyndsay A., Kushner, Erich J., Chong, Diana C., Citrin, Kathryn M., Barber, Andrew T., Park, Youngsook, Kim, Jun-Dae, Samsa, Leigh Ann, Kim, Jongmin, Liu, Jiandong, Jin, Suk-Won, Bautch, Victoria L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114582/
https://ncbi.nlm.nih.gov/pubmed/27834400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13247
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