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The novel mitochondria-targeted hydrogen sulfide (H(2)S) donors AP123 and AP39 protect against hyperglycemic injury in microvascular endothelial cells in vitro

The development of diabetic vascular complications is initiated, at least in part, by mitochondrial reactive oxygen species (ROS) production in endothelial cells. Hyperglycemia induces superoxide production in the mitochondria and initiates changes in the mitochondrial membrane potential that leads...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharmacol Res
Päätekijät: Gerő, Domokos, Torregrossa, Roberta, Perry, Alexis, Waters, Alicia, Le-Trionnaire, Sophie, Whatmore, Jacqueline L., Wood, Mark, Whiteman, Matthew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113977/
https://ncbi.nlm.nih.gov/pubmed/27565382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.08.019
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