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Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2

Cellular senescence is a key driver of ageing, influenced by age-related changes to the regulation of alternative splicing. Hydrogen sulfide (H(2)S) has similarly been described to influence senescence, but the pathways by which it accomplishes this are unclear. We assessed the effects of the slow r...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Latorre, Eva, Torregrossa, Roberta, Wood, Mark E., Whiteman, Matthew, Harries, Lorna W.
Format: Artigo
Language:Inglês
Published: Impact Journals 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075431/
https://ncbi.nlm.nih.gov/pubmed/30026406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101500
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