AP39, a mitochondria‐targeting hydrogen sulfide (H(2)S) donor, protects against myocardial reperfusion injury independently of salvage kinase signalling

BACKGROUND AND PURPOSE: H(2)S protects myocardium against ischaemia/reperfusion injury. This protection may involve the cytosolic reperfusion injury salvage kinase (RISK) pathway, but direct effects on mitochondrial function are possible. Here, we investigated the potential cardioprotective effect o...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Karwi, Qutuba G, Bornbaum, Julia, Boengler, Kerstin, Torregrossa, Roberta, Whiteman, Matthew, Wood, Mark E, Schulz, Rainer, Baxter, Gary F
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289944/
https://ncbi.nlm.nih.gov/pubmed/27930802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13688
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