AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Increasing evidence suggests that mitochondrial functions are altered in AD and play an important role in AD pathogenesis. It has been established that H(2)S homeostasis is balanced in AD. The emerging mitochondrial roles of H(2)S include antioxidation, antiapoptosis, and the modulation of cellular...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhao, Feng-li, Fang, Fang, Qiao, Pei-feng, Yan, Ning, Gao, Dan, Yan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753001/
https://ncbi.nlm.nih.gov/pubmed/27057285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8360738
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