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AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons
Increasing evidence suggests that mitochondrial functions are altered in AD and play an important role in AD pathogenesis. It has been established that H(2)S homeostasis is balanced in AD. The emerging mitochondrial roles of H(2)S include antioxidation, antiapoptosis, and the modulation of cellular...
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| Pubblicato in: | Oxid Med Cell Longev |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753001/ https://ncbi.nlm.nih.gov/pubmed/27057285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8360738 |
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